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Course details

  • Duration

    18 h 0 m
  • Language


(100-OD) Introduction to Phoenix WinNonlin

Cost - $1,595 (Academia $798)

The focus of this course is to train new and current WinNonlin users how to use Phoenix WinNonlin, and includes hands-on exercises with some discussion of theory behind the exercises. The course provides an overview of the Phoenix platform and some basic concepts such as: graphical interface, projects, object browser, workflows and navigation.

Contact for academic discount

Software Used

Phoenix WinNonlin

 A temporary license is provided to subscribers of this course.

Accessing the Course

After registering for this course, login to and see the course under the Catalog Section ‘My Courses’. 

You will have access to this course for a period of 3 years after the purchase.

The purchase is for a single seat in the course. No sharing the login between different individuals is allowed. Additional seats must be purchased if more than one person wishes to take the training course.

Course Length: 

The course provides approximately 4.5 hours of video instruction which includes a practical component that you can do at your own pace. It is expected to take participants about 18+ hours to complete, including time to perform the tasks in Phoenix.


Before attending this course, attendees should have basic knowledge of PK/PD concepts


Tom Jones

Tom Jones has helped thousands of scientists become proficient with using Certara software in their research in the pharmaceutical industry. After completing his Ph.D. in analytical chemistry, he spent several years as an assistant professor, during which time he applied molecular modeling to teaching and research in chemistry, and then came to Certara, where for 18 years he has applied his passion for teaching scientific software applications. At first Tom was focused exclusively on molecular modeling applications in drug discovery and later broadened his expertise to include informatics and PK/PD modeling and analysis. He has created many training manuals, and you may very well have heard his voice in one of the numerous webinars and video demos he has created to help scientists become more proficient with Certara software.

Training material

  • Welcome!
  • Course Navigation
  • Course Materials
  • How to get help
  • Questions
  • Tip: How to set video quality
  • Course Introduction
  • Phoenix 8 Updates
    • Interface Changes in Phoenix 8
    • New NCA Parameters in Phoenix 8 (Part 1)
    • New NCA Parameters in Phoenix 8 (Part 2)
    • Locking Workflows in Phoenix 8
    • Saving Object Settings
  • Exercise 1: Manage Data
    • EX1-1: Create Project (Manage Data)
    • EX1-2: Import a File
    • EX1-3: Rename a Column
    • EX1-4: Move a Column
    • EX1-5: Sort Rows
    • EX1-6: Convert Simple Unit
    • EX1-7: Convert Complex Unit
    • EX1-8: Perform Descriptive Statistics
    • EX1-9: View History Tab and Set Preferences
  • Exercise 2: Create Plots
    • EX2-1: Project Setup (Create Plots)
    • EX2-2: Create XY Plot
    • EX2-3: Use Lattice Conditions
    • EX2-4: Use Error Bars
    • EX2-5: Modify Axis Scale and Labels
    • EX2-6: Add Reference Lines
    • EX2-7: Modify Graph Name in Legend
    • EX2-8: Control Graph Appearance
    • EX2-9: Modify Plot Layout
    • EX2-10: Create Overlay Plot
  • Case Study 1: Create Plots
    • CS1-1: Introduction to Case Study
    • CS1-2: Instructions for Case Study
    • CS1-3: Solution to Case Study
  • Introduction to NCA
  • Review of PK Parameters
  • Exercise 3: Perform Plasma NCA
    • EX3-1: Project Setup (Perform Plasma NCA)
    • EX3-2: Create NCA Object
    • EX3-3: Specify Dosing
    • EX3-4: Execute NCA Best Fit
    • EX3-5: Duplicate NCA Object
    • EX3-6: Specify User-Selected Time Points
    • EX3-7: Examine Slopes
    • EX3-8: Compute Partial Areas
    • EX3-9: Therapeutic Range
    • EX3-10: Specify Preferred Units
    • EX3-11: Specify Parameter Names
    • EX3-12: Create Simple Table
  • Exercise 4: Perform Urine NCA
    • EX4-1: Project Setup (Perform Urine NCA)
    • EX4-2: Set up Urine NCA
    • EX4-3: Specify Dosing
    • EX4-4: Execute Urine NCA
  • Exercise 5: Perform NCA on Sparse Data
    • EX5-1: Project Setup (Perform NCA on Sparse Data)
    • EX5-2: Set up the NCA Analysis
    • EX5-3: Execute the NCA
  • Exercise 6: Use Data Tools
    • EX6-1: Project Setup (Use Data Tools)
    • EX6-2: Append Worksheets
    • EX6-3: Pivot Worksheet
    • EX6-4: Split Worksheet
    • EX6-5: Stack Columns
    • EX6-6: Merge Worksheets
    • EX6-7: Data Wizard Column Transformation
    • EX6-8: Data Wizard Column Properties
    • EX6-9: Data Wizard Filter
  • Exercise 7: Use Workflow Templates
    • Note to users of Phoenix 8
    • EX 7-1: Project Setup (Use Workflow Templates)
    • EX7-2: Create Object Template
    • EX7-3: Create Workflow Template
    • EX7-4: Apply Workflow Template
  • Using Multiple Dose Types in NCA
  • Introduction to Case Studies 2A and 2B
  • Case Study 2A: Bioavailability
    • CS2A-1: Case Study Instructions
    • CS2A-2: Solution Part 1 - Project Setup
    • CS2A-3 Solution Part 2 - Perform NCA
    • CS2A-4 Solution Part 3 - Pivot NCA Results
    • CS2A-5 Solution Part 4 - Determine BA
  • Case Study 2B: Renal Clearance
    • CS2B-1 Case Study Instructions
    • CS2B-2: Solution Part 1 - Project Setup
    • CS2B-3: Solution Part 2 - Plasma and Urine NCA
    • CS2B-4: Solution Part 3 - Compute Renal Clearance
  • Exercise 8: Manage Non-Numeric Data (BQL)
    • EX8-1: Unconditional Substitution (BQL)
    • EX8-2: Conditional Substitution (BQL)
    • EX8-3: Set to LLOQ and Censor (BQL)
  • Exercise 9: Tables
    • EX9-1: Create Simple Table
    • EX9-2: Row Stratification
    • EX9-3: Column Stratification
    • EX9-4: Add Statistics
    • EX9-5: Set Precision
    • EX9-6: Format Column Headers
    • EX9-7: Change Column Order
  • Exercise 10: Nonparametric Superpositioning
    • EX10-1: Project Setup (Nonparametric Superpositioning)
    • EX10-2: Setup Nonparametric Superposition
    • EX10-3: Use Variable Dosing
    • EX10-4: Use Regular Dosing
  • Exercise 11: Export Data
    • EX11-1: Export to Word
    • EX11-2: Export to SAS Transport File
    • EX11-3: Export Plot via Copy/Paste
    • EX11-4: Export to Excel
    • EX11-5: Export to CSV File
  • Exercise 12: Bioequivalence
    • EX12-1: Project Setup (Bioequivalence)
    • EX12-2: Run NCA
    • EX12-3: Evaluate BE (for FDA)
    • EX12-4: Evaluate BE (for EMA)
  • Intro to Compartmental PK Modeling
  • Review of Compartmental Models
  • Exercise 13: Create PK Model (using WNL5 Classic Model)
    • EX13-1: Project Setup (Classic PK Model)
    • EX13-2: Create PK Model
    • EX13-3: Execute PK Model
  • Exercise 14: Create PK Model (using Phoenix Model)
    • EX14-1: Setup PK Model (Phoenix Model)
    • EX14-2: Execute PK Model
    • EX14-3: Evaluate Model Output
  • Residual Error Models
  • Review of Residual Error Models
  • Exercise 15: Determine Optimal Number of Compartments
    • EX15-1: Project Setup (Number of Compartments)
    • EX15-2: Create 1C Model
    • EX15-3: Create 2C Model
    • EX15-4: Compare Models
  • Exercise 16: Simulate using PK Model
    • EX16-1: Project Setup (Simulation)
    • EX16-2: Setup Simulation
    • EX16-3: Run Simulation
  • Optional Exercises
    • Exercise 17: Create PD Model
      • EX17-1: Project Setup (PD Model)
      • EX17-2: Simple Emax Model
      • EX17-3: Sigmoid Emax Model
    • Intro to PK/PD Modeling - Using an Effect Compartment
    • Exercise 18: Create PK/PD Model
      • EX18-1: Project Setup (PK/PD Model)
      • EX18-2: Create PK Model
      • EX18-3: Execute PK Model
      • EX18-4: Create PK/PD Model
      • EX18-5: Semicompartmental Model
      • EX18-6: Execute PK/PD Model
      • EX18-7: Simulate PK/PD
    • Course Recap
    • End of On-Demand Course Survey v2