Description
March-April 2026
Cost - $550 (Academia $275, Africa/India $150)
Certification Course Overview
This certification course focuses on compartmental PK/PD modeling using Phoenix WinNonlin. Participants will learn to build and customize Maximum Likelihood models, evaluate model adequacy, and use simulations to inform dosing decisions. The course emphasizes hands-on experience with Phoenix’s Graphical Model Editor and includes both theoretical and practical components.
Course Structure
Total Duration: 18 hours of live sessions + 5 self-paced exercises
Live Components:
- 6 × 2-hour lecture/demo sessions
- 6 × 1-hour hands-on group exercises
Access: Recordings available for 3 months post-course
Prerequisites
Familiarity with Phoenix and basic PK concepts is recommended.
Suggested prep courses:
(122-LIVE-CERT) Phoenix WinNonlin (Part 1) NCA Certification Course
(103-OD) Fundamentals of Pharmacokinetics
2026 Live Sessions
- Lecture/Demo: Tuesdays, March 10 – April 14 (10AM–12PM ET)
- Hands-on Exercises: Fridays, March 13 – April 17 (11AM–12PM ET)
Who Should Attend
This course is ideal for:
- Scientists and analysts working in pharmacokinetics, pharmacodynamics, or pharmacometrics
- Clinical pharmacologists seeking to learn PK/PD modeling skills
- Professionals using Phoenix WinNonlin for drug development or regulatory submissions
- Academic researchers and graduate students who work with drug development
- Anyone who has completed the NCA certification course and wants to develop skills in modeling and simulation
Certification Exam
Software: No installation required; interactive simulation based on Phoenix WinNonlin 8.4/8.5
Structure: Two parts
- Part 1: 1 hr 45 min
- Part 2: 75 min
Content: 80–90 questions covering theory and practical application
Passing Score: 75% on both parts
Attempts: Two included
Topics: PK/PD theory, model building, simulations, error models, graphical/textual model editing
Time Commitment
Estimated 5 hours/week for live sessions and assignments, plus up to 6 hours for the certification exam
Software Requirements
Phoenix WinNonlinTM license required
Participants are expected to have a current license to Phoenix WinNonlin. If a 60-day software license is needed one can be provided for an additional fee. Contact us if you want to order a license.
Pricing
Cost - $550 (Academia $275, Africa/India $150)
Users requesting an Academic membership will only be accepted with proof of academic status by using an active academic email address. Users from Africa/India will need to provide Certara University with a copy of their government issued proof of residency. If an email address fails to meet that standard, the individual will be notified and will not be given access to the requested membership type.
Session Topics
Week 1 main session: Course overview, motivation for modeling and simulation, introduction to PK modeling, exploratory data analysis, introduction to the Maximum Likelihood Model object.
Week 1 hands-on exercise session: Examine results of IV-bolus model (previously executed), examine results of PO model (previously executed).
Week 2 main session: Review of PK modeling, structural models (administration, time lag, number of compartments, etc.), secondary parameters, data structure for compartmental modeling
Week 2 hands-on exercise session: Create 1-compartment IV-bolus model, create 2-compartment IV-bolus model, decide which model better fits the data.
Week 3 main session: How to obtain initial estimates, residual error models, interpretation of model results.
Week 3 hands-on exercise session: Create 1- and 2-compartment models for the PO data, compare models and decide which better fits the data, determine the best residual error model for the data.
Week 4 main session: simple simulations, comparing models, how to report individual modeling results.
Week 4 hands-on exercise session: Create a basic simulation, create a simulation using ADDL, develop a safe and efficacious dosing regimen.
Week 5 main session: Simulations (NPS, ADDL and SS), graphical model editor (including a simple TMDD).
Week 5 hands-on exercise session: Use graphical editor to create IV/PO model, determine bioavailability.
Week 6 main session: Advanced topics (modeling metabolites, selection of time points, troubleshooting, text mode), demo of PD, discuss population modeling, quick demo of naive pooled population model, closing remarks.
Week 6 hands-on exercise session: Use graphical model editor, use textual model editor.
Objectives
- Understand the motivation and principles behind pharmacokinetic (PK) modeling and simulation, including its role in drug development and decision-making.
- Perform exploratory data analysis (EDA) to assess data quality and prepare for modeling.
- Use the Maximum Likelihood Model object to build and evaluate PK models.
- Generate initial parameter estimates for PK models
- Interpret model outputs to assess goodness-of-fit and make informed decisions about model selection.
- Conduct simulations to explore dosing regimens, including multiple-dosing to steady state
- Use graphical and textual model editors to build and modify models, including advanced structures like TMDD and metabolite modeling.
- Report individual modeling results clearly and effectively for scientific and regulatory audiences.
Certificate
By completing/passing this course, you will attain the certificate Certificate of Completion
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Cancellation Policy
Classroom Courses
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If a scheduled class is cancelled, Certara will notify enrolled students at least thirty calendar days before the first day of the scheduled class and the full cost of the course would be refunded. Certara will not be responsible for any airfare, accommodation or other costs incurred by registrants in the event a course is cancelled for any reason. If Certara cancels a course within 30 days for any unforeseen reason a full refund will be issued and airfare exchange fees may be refunded.
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Notification of Cancellation by Participant Amount of Refund| 1-30 Calendar Days | 0% Refund |
| 31-59 Calendar Days | 50% Refund |
| 60 Calendar Days or More | 100% Refund |
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