[307-FL] NONMEM to NLME Webinars

Content
13 modules

Difficulty
Advanced

Rating

Course Length
8 hours

Instructor
Tom Jones

Price
Free

Description

This is an archive of the NONMEM to NLME webinars that were presented during 2018. The goal is to demonstrate how to convert NONMEM models into Phoenix. A range of scenarios is covered ranging from PK and PKPD to categorical response and TMDD models. All sessions include a detailed discussion of the translation from NM-TRAN to PML code as well as how to setup and run NONMEM and Phoenix NLME models, finishing with a comparison of the two model results.

1.
PK 1-Compartment IV Bolus Model FOCE
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2.
PK 2 compartment multiple dose- IV bolus Plasma and Urine QRPEMIMP
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3.
PK 2 compartment oral with Disease State covariate on V and CL
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4.
PK Nonlinear Elimination and Model Validation I Bootstrap
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5.
Mixed Absorption and Model Validation II VPC
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6.
Running NONMEM and Phoenix NLME in the Cloud
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7.
PD Emax inhibitory with baseline and shape factor
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8.
PD Indirect Response with IV Bolus Dosing
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9.
PK/PD 1 Compartment-IV Infusion - Emax with Baseline, Shape and Effect
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10.
Comparisons PD Categorical Response Analysis
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11.
Comparisons PD Time-to-Event Analysis
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12.
Comparisons PD Count Analysis
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13.
TMDD Model translated from NONMEM (NM-TRAN) to Phoenix NLME (PML)
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