(205-OD) Customizing PK/PD Models: Graphical and PML

12 modules



Course Length
12 hours

Tom Jones

$250 - 500


Cost - $500 (Academia $250, India $125)

Course Description

This course is intended for Phoenix users who want to extend beyond library models, to model their own data.  It provides a solid foundation and a structured approach to model building, to create your own PK and PK/PD models. 

This highly practical course gives an accelerated introduction to customizing models with both the Graphical and Textual model editors in Phoenix.  It assumes that you have ideas for PK and/or PK/PD models that you want to construct, and you mainly need to know how to implement them in either the Graphical or Textual modes.  The course includes a basic introduction to PK/PD modeling and population PK modeling.

There are about 3 hours of video in the course, plus interactive exercises.  You should expect to spend about 12 hours of work to finish.  You will have access to this course for a period of 3 years after purchase.

If you are an academic user, please contact us so we can update your account profile to give you access to academic pricing.  Note that you must register with an email address that is associated with an academic institution to get academic pricing.

If you are located in India, please contact us so we can provide a coupon that will give 75% off the full price of the course.  You will need to provide proof that you are physically located in India to get the coupon.


Learners who take either the e-learning course (100-OD) Introduction to Phoenix WinNonlin or the live online course (123-LO) PK Modeling and Simulation using Phoenix WinNonlin should have sufficient background to take this course. 

Alternatively, learners should have knowledge/skills in the following areas:

  • Knowledge of basic concepts of PK models
  • Using Phoenix PK Library models (i.e., using the built-in options)
  • Obtaining initial estimates for PK models (using NCA or other methods)
  • Evaluating the fit of PK models

Other Related Courses

The following courses provide a deeper theoretical background, and provide a good complement to this course:


You will learn to do the following:

  1. Edit a PK model using the Graphical Model Editor in Phoenix.  Add compartments, dose points, flow, observations, parameters, procedures and expressions in graphical mode.
  2. Given a model diagram, write the differential equations that describe that model.
  3. Given a set of differential equations, write the PML code for an individual PK model using the Textual Model Editor in Phoenix.
  4. Given an individual PK model, convert the PML code into a population PK model, using the Textual Model Editor in Phoenix.
  5. Write the PML code necessary to convert a PK model to a PK/PD model (including direct PK/PD, effect compartment models and turnover models, using the Textual Model Editor in Phoenix.


By completing/passing this course, you will attain the certificate Certificate of Completion

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Course Overview
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Edit PK Models Graphically
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Write Differential Equations
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Suggested Modeling Activity 1
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Write PML Code for Individual PK Models
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Write PML Code for Population Models
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Edit PK/PD Models Graphically
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Write PML code for PK/PD Models
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Suggested Modeling Activity 2
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End of Course Survey
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Added about 2 months ago, by Ahmed
Added 8 months ago, by Sara Carolina
Very good course! Highly recommend it!
Added 11 months ago, by Sijia
Added 11 months ago, by UNC Eshelman School
Added over 1 year ago, by Keith

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